I had three injections all of which worked for a few days to two weeks then stopped. The excruciating pain returned and only Vicoden 5 mg 3-4 times a day controlled the pain. Vicoden at that dose is the lowest dose prescribed. it worked perfectly for several years and doctors refused to prescribed opioids for fear of losing their license. My sister recently died of throat cancer and she complained constantly of pain. She died with unrelieved pain. As a cancer patient she was prescribed Morphine 2 mg. every 6 hours. That is beyond ridiculous but keeps our doctor’s license safe. Our doctors are violating their Hippocratic oath – Do No Harm. They had added a caveat “except when the government is breathing down your neck. Then the patient be damned. I am glad this helped you Randy. I don’t know your clinical status but I am sure it differs from mine. Do you have severe and crippling arthritis?
Drugs which induce cytochrome P450 3A4 (CYP 3A4) enzyme activity (., barbiturates, phenytoin, carbamazepine, rifampin) may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. Drugs which inhibit CYP 3A4 (., ketoconazole, macrolide antibiotics such as erythromycin) have the potential to result in increased plasma concentrations of corticosteroids. Dexamethasone is a moderate inducer of CYP 3A4. Co-administration with other drugs that are metabolized by CYP 3A4 (., indinavir, erythromycin) may increase their clearance, resulting in decreased plasma concentration.
Inform your physician of all the medications you take (prescription and over the counter) and other medical conditions you have before taking a Medrol Dose Pack. If you are scheduled for surgery, the medical staff must be aware that you are on a Medrol Dose Pack. It never should be taken if you are allergic to methylprednisolone or have a fungal infection. Since steroids can weaken the immune system, avoid people who have colds and the flu. Contact your physician if you become exposed to the measles or chicken pox, as these illnesses can become serious when a person is on steroid medication.