My 7 year old son was stung by a bee about 2- weeks ago, on the side of his knee. It swelled up really big the next day, and caused a slight limp, and ended up getting a couple of small blisters. It all healed itself within a few days and he went back to being his normal, active self. About a week and a half ago, he started complaining of pain in the same leg. At first it wasn’t too bad, and I didn’t give much attention to it (I figured it was one of the many pains my kids always complain about but never amount to anything and they forget about it). Gradually, it got worse, and he began to limp and complain more frequently. Took him to the doctor, who did an x-ray and blood work. All tests came back normal, so we had him take it easy on that leg and rest a bit. Still though, his leg got worse, to the point where he can’t walk on it, so we took him to the ER two days ago. X-rays, blood work, ultrasound… all normal. No fever, no swelling, or anything else. He was given a boot for his leg, in case he has a micro fracture. The boot helped for a day, but now his pain is so bad, he can’t walk with the boot and he can’t move his leg hardly at all. We are going to take him back to the doctor in the morning, but can’t fathom what might be going on. Could the bee sting and these symptoms be at all related??? I feel like the answer is no, but we are at a loss for what might be wrong with him.
MSG is not dangerous, it’s industrial and in many processed foods that are bad for you. I’m not going to worry about an occasional dab of it, especially considering I use a lot of high glutamate traditional foods in my own kitchen such as fermented seafood pastes and stocks. It should be noted that scientists like Olney who have written about the dangers of excitotoxins in developing children also recognize these traditional high-glutamate foods could be dangerous. I doubt it, but I will refrain from injecting them into the brains of my offspring though.
The pharmacokinetics of Tamsulosin hydrochloride have been compared in 6 subjects with mild-moderate (30 ≤CL cr <70 mL/min/ m 2 ) or moderate-severe (10 ≤CL cr <30 mL/min/ m 2 ) renal impairment and 6 normal subjects (CL cr >90 mL/min/ m 2 ). While a change in the overall plasma concentration of Tamsulosin hydrochloride was observed as the result of altered binding to AAG, the unbound (active) concentration of Tamsulosin hydrochloride, as well as the intrinsic clearance, remained relatively constant. Therefore, patients with renal impairment do not require an adjustment in Tamsulosin Hydrochloride Capsules dosing. However, patients with end-stage renal disease (CL cr <10 mL/min/ m 2 ) have not been studied [ see Use in Specific Populations () ].