Tb meningitis steroids

Inflammation of the meninges may lead to abnormalities of the cranial nerves , a group of nerves arising from the brain stem that supply the head and neck area and which control, among other functions, eye movement, facial muscles, and hearing. [2] [15] Visual symptoms and hearing loss may persist after an episode of meningitis. [2] Inflammation of the brain ( encephalitis ) or its blood vessels ( cerebral vasculitis ), as well as the formation of blood clots in the veins ( cerebral venous thrombosis ), may all lead to weakness, loss of sensation, or abnormal movement or function of the part of the body supplied by the affected area of the brain. [2] [3]

Tuberculous meningitis is an inflammation of the meninges, which are membranes that envelope a person's brain and the spinal cord. It is caused by infection with one of several mycobacterial species that belong to the Mycobacterium tuberculosis complex, which are responsible for tuberculosis (TB) disease. Tuberculous meningitis is a severe form of TB and accounts for many deaths ( Tandon 1988 ). It is a form of extrapulmonary TB (that is, TB that occurs outside the lungs). The World Health Organization (WHO) reported that million of the million new TB cases reported worldwide in 2013 were extrapulmonary cases ( WHO 2014 ). There is an association between extrapulmonary TB and human immunodeficiency virus (HIV) infection, particularly in people with low CD4 cell counts ( Naing 2013 ). It appears that the higher risk of TB infection in HIV-positive people means that tuberculous meningitis is also more common in this group ( Berenguer 1992 ; Berger 1994 ).

At follow-up from three to 18 months, steroids reduce deaths by almost one quarter ( RR , 95% CI to ; nine trials, 1337 participants, high quality evidence ). Disabling neurological deficit is not common in survivors, and steroids may have little or no effect on this outcome ( RR , 95% CI to ; eight trials, 1314 participants, low quality evidence ). There was no difference between groups in the incidence of adverse events, which included gastrointestinal bleeding, invasive bacterial infections, hyperglycaemia , and liver dysfunction.

It is recommended that prophylactic antibiotic therapy be taken prior to certain dental and urological procedures for 2 years post-implantation. In patients with inflammatory arthritis, those who are  receiving immunosuppression treatment, patients with insulin-dependent diabetes, those with  a history of prior prosthetic joint infection, hemophilia or who suffer from malnutrition, it is recommended that prophylactic antibiotic therapy be given prior to certain dental and urological procedures for life. If any of the above conditions apply to you, you should discuss this with your dentist or your urologist.

Tb meningitis steroids

tb meningitis steroids

It is recommended that prophylactic antibiotic therapy be taken prior to certain dental and urological procedures for 2 years post-implantation. In patients with inflammatory arthritis, those who are  receiving immunosuppression treatment, patients with insulin-dependent diabetes, those with  a history of prior prosthetic joint infection, hemophilia or who suffer from malnutrition, it is recommended that prophylactic antibiotic therapy be given prior to certain dental and urological procedures for life. If any of the above conditions apply to you, you should discuss this with your dentist or your urologist.

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